Heat Shock Protein 70 Enhances Vascular Bone Morphogenetic Protein-4 Signaling by Binding Matrix Gla Protein
نویسندگان
چکیده
منابع مشابه
Heat shock protein 70 enhances vascular bone morphogenetic protein-4 signaling by binding matrix Gla protein.
RATIONALE Matrix Gla protein (MGP) is a calcification inhibitor, which binds and inhibits bone morphogenetic protein (BMP)-2 and -4. OBJECTIVE The objective was to determine whether MGP also binds other proteins, which could interfere with its function. METHODS AND RESULTS We transfected bovine aortic endothelial cells with N-terminally FLAG-tagged MGP and used immunoprecipitation and liqui...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2009
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.109.202333